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Description
Comparing GLP type therapies for weight loss in those without diabetes. Two glucagon like peptide 1 receptor agonists (GLP 1 RAs) (#semaglutide and #liraglutide) and one dual agonist (#tirzepatide) have been FDA approved for #weightloss in adults Mechanism of action for GLP 1R agonists. Primarily expressed in the Download Scientific Diagram IBX members face GLP 1 drug costs after insurance change WHYY GLP 1 Use Associated with Lower Osteoporosis Risk in Adults with Type 2 Diabetes but Higher Risk in Adults Without Diabetes GLP 1s: Real Stories From People With Bipolar Disorder bpHope.com Your guide to GLP 1 side effects WW USA
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4.0 ★★★★★
Based on 421 reviews
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Product Reviews
★★★★★ 5
Great quality & interest
Keeps my Shepard/Husky occupied for 30+ minutes. She hasn't even destroyed it.
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Reviewed in the United States on August 10, 2025
★★★★★ 4
Good for medium and large dogs not good for small dogs
Too big for dogs under 15 pounds. Treats are hard to get out of the four corners. My dog can barely pick this up. She weighs 12 pounds. She still found it interesting though trying to dig the treats out that she was unsuccessful. Even after I cut all the little triangle prongs off the four corners the treats are still stuck in there. There is a slot on the side that I can put half of a dental refill in the side and she can eventually get it out so there’s still somewhat of play and challenge received, but not that satisfied to me.
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Reviewed in the United States on October 3, 2025
★★★★★ 5
Great for aggressive chewers!
Size: Jumbo, Style: Peanut Butter
I have a very very aggressive chewer. She is a Rottweiler/Pitbull mix. Most toys she completely destroys within 2 days, sometimes 2 hours. I must praise this toy as she has had it for over 5 months and has not destroyed it! She loves chewing the ends and carries in her mouth squeaking it as she goes. I have 4 pups and they all take turns chewing when they can. I will be buying more Playology dog toys in the future.
Thank you for making such a great toy!!
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Reviewed in the United States on April 26, 2026
★★★★★ 5
They are her favorites
Size: Medium (VALUE 2-Pack), Style: Beef, Size: Medium (VALUE 2-Pack), Style: Beef
We’ve had many dogs, many very destructive ones and wish I had these years ago. The hard toys get sharp edges, this toy is the best and yes is far better than the other red ones. My bulldog wants tug of war for 30 min to an hour every night. We’ve gotten tennis elbow, tendinitis, and pulled muscles holding onto this thing. She has tons of toys but 9pm and this is only option for her. We don’t get a choice. Easy to hold, well for a few min until your hand gets tired. First you one was about 3 years ago and she’s only on her third one. They last forever, easy to clean, and aren’t sharp edges. Seriously, better than any toy sold anywhere. My phone has hundred of pictures of Pickle holding this. She’s doing it right now. If you have a strong destructive dog that takes pride in destroying toys, ruin their confidence and get them this one.
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Reviewed in the United States on April 5, 2026
★★★★★ 5
Perfect Toy for Large Dogs
Size: Medium, Style: Cheddar Cheese
I don’t normally leave reviews, but this toy is stellar and is a new favorite for my dog! She is a large dog (70lbs cattle dog lab mix) and I accidentally bought a medium, but it actually is a great size for her! So far this stands up to her chewing, but I may need to update in a few weeks to speak for durability but it really does feel solid. Most toys don’t last an afternoon once she starts chewing, so this has already won in that regard. The shape is perfect as well. She can gnaw at it, squeak, play fetch, play tug. It bounces when she throws it around herself. The fact it smells like stinky cheese is just an added bonus for her. All around, a very well designed dog toy!
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Reviewed in the United States on December 27, 2023