CD30/TNFRSF8 Fc Chimera Protein, Mouse
SKU: 50353089028

CD30/TNFRSF8 Fc Chimera Protein, Mouse

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Description

CD30/TNFRSF8 Fc Chimera Protein, MouseProduct Specification Species Mouse Synonyms CD30; CD30KI 1; CD30L receptor; D1S166EKi 1; TNFRSF8 Accession Q60846 Amino Acid Sequence Phe19 Thr281, with C hIgG Fc Expression System HEK293 Molecular Weight 72 95kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <0. 1EU g Physical Appearance Lyophilized Powder Storage Buffer PBS, 5% trehalose, PH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid

Product Specification


Species Mouse
Synonyms CD30; CD30KI-1; CD30L receptor; D1S166EKi-1; TNFRSF8
Accession Q60846
Amino Acid Sequence Phe19-Thr281, with C-hIgG Fc
Expression System HEK293
Molecular Weight

72-95kDa (Reducing)

Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Physical Appearance Lyophilized Powder
Storage Buffer PBS, 5% trehalose, PH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1. Oflzoglu E. et al. (2009) Adv. Exp. Med. Biol. 647:174
2. Kennedy, M.K. et al. (2006) Immunology 118:143.
3.Tarkowski, M. (2003) Curr. Opin. Hematol. 10:267.

Background

CD30, also known as Ki-1 antigen and TNFRSF8, is a 120 kDa type I transmembrane glycoprotein belonging to the TNF receptor superfamily. Mature mouse CD30 consists of a 264 amino acid (aa) extracellular domain (ECD) with three cysteine-rich repeats, a 27 aa transmembrane segment, and a 190 aa cytoplasmic domain. In contrast, human CD30 includes an additional 90 aa in the ECD and contains six cysteine-rich repeats. CD30 is normally expressed on antigen-stimulated Th cells and B cells. However, it is upregulated in Hodgkin’s disease (on Reed-Sternberg cells), other lymphomas, chronic inflammation, and autoimmunity. CD30 binds to CD30 Ligand/TNFSF8 which is expressed on activated Th cells, monocytes, granulocytes and medullary thymic epithelial cells. In B cells, CD30 ligation promotes cellular proliferation and antibody production in addition to the expression of CXCR4, CCL3,and CCL5. An 85 ‑ 90 kDa soluble form of CD30 is shed from the cell surface by TACE-mediated cleavage. Soluble CD30 retains the ability to bind CD30 Ligand and functions as an inhibitor of normal CD30 signaling.

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SKU: 50353089028

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4.0 ★★★★★
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M
Natrona Heights, US
★★★★★ 4
💜
my 6’4” husband wore this to our wedding. it looked amazing on him 💜 everything fit pretty good except for the jacket part; that was a little big. it may fit someone who weighs a little more but my husband weighs about 165lbs. we had to tailor it a little bit. other than that, very beautiful suit.
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Reviewed in the United States on December 19, 2025
A
Verified Purchase
Alexander aranguren
Houston, US
★★★★★ 5
Nice
Size: Large, Color: Gold, Size: Large, Color: Gold
Nice
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Reviewed in the United States on May 14, 2026
V
Verified Purchase
Vanessa E Joseph
Natrona Heights, US
★★★★★ 5
Good work
Size: Large, Color: Black
Good
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Reviewed in the United States on March 26, 2026
W
Verified Purchase
Wayne
San Leandro, US
★★★★★ 5
Mans XXL Light Baby Blue Linen Suit 6'5" 225 lbs
Mans XXL Light Baby Blue Linen Suit 6'5" 225 lbs "This suit fit me perfectly. I was unsure of fit initially so I looked at measurements carefully and selected -true to my size- On suits that arrived a size too big I used a strategy found on Google to shrink my suit. On the wash setting, set it to hottest water setting and tumble/time setting. On the dryer set it to longest hottest heat setting and two things will happen, it will take out wrinkles and be a perfect fit!
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Reviewed in the United States on February 6, 2025
C
Chicago Kev
Port Orchard, US
★★★★★ 5
4.5 Stars.. Comfy, but Really Check the Size Charts
I love the material of this suit. Very comfy fabric. Out of the box, it was WAY less wrinkled than I thought it would be. The pics I took are of the suit are straight out of the packaging. When it comes to the suit itself, I really have nothing but complements. I will note a few items on the sizing: I am 6'3", 270, and I got the 3XL. The size chart says it goes to 260lb, and I think it is right, but with a caveat... Here's why: Pants: The pants actually fit me great. There is a comfort waistband, but I don't even really need it. I generally wear a 40" jean; 38" when they go to a loose fit.. The inseam is great as well. I am either a 32" or 34", but most 32" inseams are a bit short... Jacket. I tend to wear a XXLT or a 52L from a suit shop. The shoulders of the jacket fit fine. It feels OK through the arms and chest, but it is probably 1/2 - 1" away from a comfortable ability to button the jacket at my "gut". Thus my comment about sizing. I am a bit surprised that the pants fit so well through the waist but the jacket does not fit as ideally. Still - I think I am only a few pounds away from a good fit. So I kept the 5 star review with the note as the size chart does call it out... Being so descriptive here for your benefit.
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Reviewed in the United States on October 25, 2024

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