Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 6 - Jul 11
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
GSPT1/ERF3A GST&His Protein, HumanProduct Specification Species Human Synonyms ERF3A; eRF3aFLJ38048; ETF3A; eukaryotic peptide chain release factor GTP binding subunit ERF3A; Eukaryotic peptide chain release factor subunit 3a; FLJ39067; G1 to S phase transition 1,551G9. 2; G1 to S phase transition protein 1 homolog; GST1 Accession P15170 1 Amino Acid Sequence Phe294 Asp499, with C terminal GST&His Expression System Baculovirus InsectCells Molecular Weight 51kDa (Reducing) Purity 85%
Product Specification
| Species | Human |
| Synonyms | ERF3A;eRF3aFLJ38048;ETF3A;eukaryotic peptide chain release factor GTP-binding subunit ERF3A;Eukaryotic peptide chain release factor subunit 3a;FLJ39067;G1 to S phase transition 1,551G9.2;G1 to S phase transition protein 1 homolog;GST1 |
| Accession | P15170-1 |
| Amino Acid Sequence | Phe294-Asp499, with C-terminal GST&His |
| Expression System | Baculovirus-InsectCells |
| Molecular Weight | 51kDa (Reducing) |
| Purity | ＞85% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | 50mM Tris, 20mM GSH, 5%Glycerol, pH8.0 |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | Cell. 2016 Nov 17;167(5):1229-1240.e15. |
Background
GSPT1/ERF3A mediates ETF1/ERF1 delivery to stop codons: The eRF1-eRF3-GTP complex binds to a stop codon in the ribosomal A-site.GTP hydrolysis by GSPT1/ERF3A induces a conformational change that leads to its dissociation, permitting ETF1/ERF1 to accommodate fully in the A-site. Binding of eRF1, eRF3, and GTP to pretermination complexes first induces a structural rearrangement that is manifested as a 2 nucleotide forward shift of the toeprint attributed to pretermination complexes that leads to GTP hydrolysis followed by rapid hydrolysis of peptidyl tRNA.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.1 ★★★★★
Based on 282 reviews
Sort
Product Reviews
★★★★★ 5
Cool toy. Fun for all
Color: Blue
A cool toy. entertainment for the dogs but more so for the dog parents to watch the dogs reaction. Comes with an additional rope just in case, which I loved. Only side note I would say is that the fast mood could be a little faster. My Golden retriever figured out the speed in less than 24 hours and now picks up the toy to try to chew it up, instead of chasing. With him attempting to chew on the toy in the small time I give him, there are no teeth marks yet…this toy appears to be durable. We play in short increments but enjoy the toy.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 29, 2026
★★★★★ 3
Fun toy, but not durable for large heavy chewers
Color: Orange, Color: Orange
I bought this for my 80+ pound Goldendoodle, and he absolutely loved it at first. He barked at it, chased it, and it gave him some great exercise and stimulation. It definitely kept his attention and was fun to watch him play with it.
Unfortunately, once he was able to get it in his mouth, he chewed the orange end off fairly quickly. The company does include an extra replacement piece, which is actually a great idea and appreciated. However, he ended up chewing that one up too after a few more play sessions.
This toy worked well for short-term play and entertainment, but it’s not durable enough for large dogs with strong chewing habits. I think this would be much better suited for small to medium dogs.
Great concept, but I would not repurchase for a heavy chewer.
Picture of my dog for size reference!! 🫶🐶
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 17, 2026
★★★★★ 5
My Dog Loves It!
Color: Orange
Great interactive toy for my dog! The quality is nice, no weird smell, and it keeps my dog entertained and active for a long time. Worth the price!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 21, 2026
★★★★★ 5
Good quality and definitely worth it for energetic dogs.
Color: Orange
The automatic moving and rolling action really grabs my dog’s attention, and the rope adds extra fun for chasing and playing. It helps reduce boredom and keeps my dog mentally stimulated, especially when indoors. The motion activation works well, and it’s a fun and engaging toy overall.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 3, 2026
★★★★★ 5
Great Value Toy
Color: Crinkle Duck (Blue), Size: Large, Color: Crinkle Duck (Blue), Size: Large
This toy has been one of my dog’s absolute favorites. He gets excited every time he sees it and will carry it around the house, toss it in the air, and keep himself entertained for a long time. The shape and texture seem perfect for him, and it quickly became one of his go-to toys over everything else in his basket.
What I really like is that it holds up reasonably well for the price. It’s definitely not indestructible, and after a lot of play, it will sometimes start to rip—usually around the feet first since that’s where my dog tends to grab and chew the most. But honestly, considering how affordable it is, I don’t mind replacing it when needed. It’s inexpensive enough that rebuying feels worth it because he genuinely loves it that much.
I’d rather keep buying a toy he is obsessed with than spend more on something that just sits untouched. It’s fun, cute, and keeps him happy, which is what matters most. Overall, I’d definitely recommend it for dogs who love plush toys and playful chewing.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 28, 2026
recommand products
2008-2016 Nissan GTR R35 CBA DBA NISMO Ver17 Style Front Bumper
2375.00
2009-2012 Porsche Cayman 987 TEK Style Carbon Fiber Front Lip
325.00
2017-2023 Nissan GTR R35 EBA OEM Style Carbon Fiber Hood
900.00
2011-2014 Porsche Cayenne 958.1 LM Style Full Wide Body Kit
3000.00
2018-2022 Ferrari 488 Pista OEM Style Carbon Fiber Front Bumper Vent Canards
500.00